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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APBB1 All Species: 21.52
Human Site: S52 Identified Species: 52.59
UniProt: O00213 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00213 NP_001155.1 710 77244 S52 V G P K D L R S A M G E G G G
Chimpanzee Pan troglodytes XP_521814 848 91186 S185 V G P K D L R S A M G E G G G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534037 724 78741 S52 V G P K D L R S A M G E G G G
Cat Felis silvestris
Mouse Mus musculus Q9QXJ1 710 77450 S52 V V P K D L R S A M G E G S V
Rat Rattus norvegicus P46933 711 77638 S52 V V P K D L R S A M G E G S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507097 616 68316 P26 K R S Q L I I P I P S L G D Q
Chicken Gallus gallus XP_420735 740 81441 S52 P N T L S L R S S H N E L L N
Frog Xenopus laevis NP_001087003 610 66956 K20 P S E Q T K P K W Y K E G Q N
Zebra Danio Brachydanio rerio XP_693392 869 95380 S155 Y A L T S I Q S A M G L G E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787988 848 93773 T57 M D S D F S Q T D N K N E G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.6 N.A. 78.3 N.A. 94.6 93.8 N.A. 38.8 45 51.5 39.5 N.A. N.A. N.A. N.A. 31
Protein Similarity: 100 83.7 N.A. 80.6 N.A. 97.1 96 N.A. 53.6 60.9 62.2 53.5 N.A. N.A. N.A. N.A. 47.1
P-Site Identity: 100 100 N.A. 100 N.A. 80 80 N.A. 6.6 26.6 13.3 40 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 80 80 N.A. 20 33.3 20 53.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 60 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 50 0 0 0 10 0 0 0 0 10 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 70 10 10 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 30 0 0 0 0 0 0 0 0 60 0 80 40 40 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 20 10 0 10 0 0 0 0 0 0 % I
% Lys: 10 0 0 50 0 10 0 10 0 0 20 0 0 0 0 % K
% Leu: 0 0 10 10 10 60 0 0 0 0 0 20 10 10 0 % L
% Met: 10 0 0 0 0 0 0 0 0 60 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 10 10 10 0 0 20 % N
% Pro: 20 0 50 0 0 0 10 10 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 20 0 0 20 0 0 0 0 0 0 10 10 % Q
% Arg: 0 10 0 0 0 0 60 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 20 0 20 10 0 70 10 0 10 0 0 20 0 % S
% Thr: 0 0 10 10 10 0 0 10 0 0 0 0 0 0 0 % T
% Val: 50 20 0 0 0 0 0 0 0 0 0 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _